Neuroligin 3 anticorps (C-Term)

N° du produit ABIN7233050

L’anticorps Souris Monoclonal anti-Neuroligin 3 a été validé pour WB, IHC et IF/ICC. Il convient pour détecter Neuroligin 3 dans des échantillons de Rat.

Aperçu rapide pour Neuroligin 3 anticorps (C-Term) (ABIN7233050)

Antigène: Neuroligin 3 (NLGN3)

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuroligin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

Clone: S110-29

Détail du produit anti-Neuroligin 3 anticorps

Épitope: AA 730-848, C-Term

Fonction: Anti-Neuroligin-3 Mouse Monoclonal Antibody

Specificité: This antibody recognizes human, mouse and rat Neuroligin-3. It does not cross- react with Neuroligin-1, -2, or -4.

Réactivité croisée: Humain, Souris, Rat

Immunogène: Fusion protein corresponding to aa 730-848 (intracellular C-terminus) of rat Neuroligin- 3. This sequence is 99

Isotype: IgG1

Information d'application

Indications d'application: Immunoblotting: use at 1-5 μg/mL. A band of ~110 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their application.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: This product is stable for at least one (1) year at -20°C.

Détails sur Neuroligin 3

Antigène: Neuroligin 3 (NLGN3)

Autre désignation: Nlgn3

Sujet: Neuroligin-3,Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. {PubMed:17897391}.,Neuroligin-3 is a neuronal cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. It plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. It may also promote the initial formation of synapses and play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse. Note=Detected at both glutamatergic and GABAergic synapses.,Gliotactin homolog

UniProt: Q62889

Pathways: Synaptic Membrane